ProSep Blog Posts
When to Transition from Batch to Multicolumn Chromatography
When to Transition from Batch to Multicolumn Chromatography In downstream purification, selecting the optimal separation strategy directly impacts process yield, purity, throughput, and overall operational expenditure (OpEx). For decades, single-column batch chromatography has been the traditional standard across laboratories and industrial process lines. However, as processing demands intensify and efficiency margins tighten, continuous and semi-continuous […]
High-Efficiency SMB and Multicolumn Chromatography for Organic Acid Purification
High-Efficiency SMB and Multicolumn Chromatography for Organic Acid Purification In modern bioprocessing and chemical production, the efficient purification of organic acids-such as lactic, citric, and fumaric acids-is critical for achieving market-ready purity at scale. While traditional separation methods exist, the industry is increasingly turning toward Simulated Moving Bed (SMB) and multicolumn liquid chromatography (LC) to […]
Revolutionizing Food and Beverage Analysis: The Power of Reverse Phase Chromatography
Revolutionizing Food and Beverage Analysis: The Power of Reverse Phase Chromatography The food and beverage industry has been evolving continuously with a single aim to offer safe and high-quality products. To validate food products, one of the most widely used techniques includes Reverse Phase Chromatography (RPC). This analytical technique helps scientists and manufacturers to identify […]
Case Study: Optimization of Rare Sugar Production for Leading Sugar Company
Case Study: Optimization of Rare Sugar Production for Leading Sugar Company Overview This sugar processor is a leading company specializing in the production of rare sugars. They are committed to delivering high-quality sweeteners through efficient and sustainable processes. However, challenges in their existing chromatography system prompted the need for an optimized solution to improve purity, […]
Revolutionizing Petrochemicals: Unleashing the Power of Simulated Moving Bed Chromatography
Revolutionizing Petrochemicals: Unleashing the Power of Simulated Moving Bed Chromatography Simulated Moving Bed Chromatography (SMBC) sets a new standard for operational excellence in the petrochemical industry by optimizing yield and purity while slashing energy consumption. As the industry grapples with sustainability challenges, could SMBC be the key to aligning economic and environmental goals seamlessly? Schedule […]
Applications of Simulated Moving Bed Chromatography in the Food and Beverage Industry
Applications of Simulated Moving Bed Chromatography in the Food and Beverage Industry Simulated Moving Bed chromatography continues to redefine the landscape of the food and beverage industry by offering unparalleled precision in purification processes. This innovative technology facilitates the isolation of high-purity compounds such as sugars, sweeteners, and organic acids, thereby ensuring that end products […]
University College London Phoenix System Case Study
University College London Phoenix System Case Study The University College London originally acquired the Phoenix system for a 16 column separation process that was the basis for a PhD student’s thesis. The Thesis subject was the investigation of Simulated Moving Bed Chromatography for purification of protein mixtures. SMB (Simulated Moving Bed) Chromatography is a technique […]
BOSS Case Study Using the Phoenix System
BOSS Case Study The Problems In Our Industry -Inefficient purification processes -Isolate waste material building up all over the US -Synthetically made cannabinoids from dangerous reactions -Extraction and purification that uses deadly chemicals -Isolate that does not give consumers the desired effects -Everything is run as a batch process instead of continuous After Phoenix -Efficiently […]